- College Week
- Student Government Association
- African American Association
- American Dental Hygienists
- Anime Gaming Club
- Art Club
- College Republicans
- Collegiate FFA
- Communications Club
- Auto Collision Club
- Basketball Club
- Campus Christian Club
- Circle K of South Florida State College
- College Democrats
- Dental Students Association
- DeSoto Campus Ambassadors
- EMS Student Association
- Hardee Campus Ambassadors
- Health Occupations Students of America
- Hispanic Students Organization
- Honors Ambassadors
- Jac Pac
- Performing Arts Club
- Phi Beta Lambda
- Phi Theta Kappa
- Radiography Club
- Rotaract
- Soccer Club
- Student Nurses Association
- Student Practical Nurses
EMS Student Association
The EMS Student Association promotes professionalism in the field of emergency medical services and provides trainees with an avenue to become involved with emergency medical health care issues and activities beyond the classroom..
